Metronidazole & panacur side effects...

we took wilbur to the vet on wednesday and they prescribed Metronidazole for his Giardia, and panacur for his whipworms.

yesterday Wilbur for the first time since the vet visit seemed to be doing great, see the videos and pictures, he was running around and playful - but late last night he vomited first his food, and then a few hours later some white stuff it looked like the medicine we gave him... however he had no signs of diarhea all day.

today when we got up he seemed really out of it and lethargic, we took him for a little walk and his diarhea was back but a little shocking for us it had what looked like white worms in it... which i take was his whipworms and his antibiotics must be working.

this afternoon hes been pretty much sleeping and ive been keeping an eye on him, he wont eat his food at all, but thankfully drinks water... now i just took for a tiny walk barely 50 yards and his diarhea was back really bad - shortly after he went he just laid down and i couldnt get him to get back up onto his feet for about 15minutes... i sat with him just rubbing his belly - i finally got him home a few minutes ago and hes drinking water but still wont eat anything... his ears feel really warm is that a sign for something?

im gonna stay up with him all night and take him to the vet first thing in the morning - but im just wondering if any other OES have had the same medicines and or side effects....

is there a sure way to make him eat anything?

thanks for listening... i dont like seeing him like this :cry:
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At this point, he's probably miserable so the fact that he isn't eating isn't surprising but I understand your concern. If it's only been today, but he's still drinking, I'd keep an eye on him and see if there's any change in his condition but I wouldn't worry too much yet. Giardia can be tough to get rid of and the whipworms are only exacerbating the situation. We've gone through giardia with all 3 dogs and my Komondor (a rescue) came with whipworms. He suffered a couple of explosions in his crate while we were out. We came home to poo all over the walls and the ceiling and him looking like he wanted to die. Luckily, the panacur knocked those suckers out fast!

Did you buy Wilbur or was he a rescue? If he's from a breeder, he should never have come to you with those sort of problems. I'd definitely contact whomever gave him to you and bring these things to their attention. You shouldn't be paying these vet bills nor should your little guy have had to go through this either.
derby had giarida for 4 months and let me tell you it took about 6 months to get him reg. the nasty bug kept coming back .. i feel for you /good luck
thanks for your comments guys - we didnt get Wilbur from a breeder, the person we got them from said that he started with the diahrea only a day before we got him...

i think for us had we known we would have asked for a fecal test that was no more than a week old - not that this would have helped wilbur, but at least we could have been prepared for the additional expense so far.

he pretty much slept through the night - and is doing a tad better this morning... he managed a little walk this morning to do his business... no no 2's at all and still minimal to no eating...

going to see how today pans out with him...
wilbursa wrote:
im gonna stay up with him all night and take him to the vet first thing in the morning - but im just wondering if any other OES have had the same medicines and or side effects....

is there a sure way to make him eat anything?

thanks for listening... i dont like seeing him like this :cry:


Oh, poor kid :cry:

Some OES can have a bad reaction to certain drugs - metronidazole being one of them. Though I would think the worms and the meds alone could make him feel less then wonderful, please mention to your vet that the MDR1 gene mutation, while not common in OES, can be found in the breed (the one that causes drug sensitivities - most notably the ivermectin & collie connection).

I don't know what panacur consists of.

How is he doing?

Kristine
It's very difficult to actually find Giardia in a stool culture. It can often be missed and require numerous cultures. I believe this is what we went through a few years ago when Emma and Darby were pups. We did so many cultures and they all came back negative for everything but high levels of bacteria. We did round after round of Metronidazole and anti-diarrhea meds. A new vet prescribed Panacur for the entire pack at the same time and that was the last of the diarrhea.

PLEASE don't take your baby on walks off your property until he's 100% cured or you'll spread this to others. It's very contagious and you need to clean up thoroughly. This link is from the Centers for Disease Control for humans but a lot applies to dogs as well- http://www.cdc.gov/ncidod/dpd/parasites ... iardia.htm

If you're concerned about the way he's acting, make a quick call to the vet for reassurance.
Quote:
today when we got up he seemed really out of it... shortly after he went he just laid down and i couldnt get him to get back up onto his feet for about 15minutes


Please call your vet to make certain he doesn't need to be seen.

Fenbendazole (Panacur Rx), is considered to be one of the safer medications
in veterinary medicine. It is usually non-toxic even at very high doses.
There is a small chance of an anaphylactic shock reaction when using
Panacur in heavily parasitized animals, but not because of the Panacur
itself. The death of large numbers of parasites at once, due to the
medication, can lead to this problem. It is very unlikely that would have
been the case for your dog, because he is old enough that natural
resistance should be helping to keep parasite numbers down, even if some
are present.
Source: http://www.vetinfo4dogs.com/deffect.htm ... 0and%20IBD
im so glad i found this site my 18wk old akita was diagnosed with giardia and worms last week,unfortunatly she had to be put to sleep on 20/09/08,due to ending up with kidney failure on top of other complications,i was told i would have to live in very squalid conditions for my dog to obtain this or contaminated water,we only had our pup at home for 8wks,6wks with the breeder and 4wks in the vets so its hard to say where she picked it up from,im very sadened by our loss i have tried to contact the breeder all to no avail,the pup seemed fine at first then got loss of apetite follwed by weight loss and tierdness she collasped and was rushed into the vets where she remained for the last 4wks of her life with various treatments and drugs.
you can get giardia from anywhere, it lives everywhere. It is fecal oral contamination. Very common at dog parks because a lot of pooping happens there but also because they share a water bowl at most places. The giardia lives in the stool so if someone has it and steps in it and brings it in your house then your dog can get it or if someone steps in it and licks their feet and its in their mouth or if that dog then goes to a communal waterbowl it can transmit that way as well. It is a narly little bug to get rid of and it can take a really long time to take care of. If your pup has so much giardia and especially whipworms, it can make them feel miserable esepeically when the whips are dying off and they are coming out. and yes they can cause them to vomit either producing worms or not but it means that the GI tract is full and the body is trying to get rid of em. Supportive care at home if he isnt too bad is good, just take it easy with him and give the meds time.
I've had two upright friends on Panacur recently and they both said the drug just knocked all the starch out of them.....they felt terrible, but knew they had to go thru this to get rid of their intestinal problems.

Try to keep the guy hydrated with liquids and broth and offer "tender tummy food" boiled rice and meat for awhile and slowly bring back his kibble.
I'm sorry to hear about the loss of your Akita puppy. Her young immune system must not have been able to battle the parasite, as usually it is treatable. :cry:
Mad Dog wrote:
[
Oh, poor kid :cry:

Some OES can have a bad reaction to certain drugs - metronidazole being one of them. Though I would think the worms and the meds alone could make him feel less then wonderful, please mention to your vet that the MDR1 gene mutation, while not common in OES, can be found in the breed (the one that causes drug sensitivities - most notably the ivermectin & collie connection).

I don't know what panacur consists of.

How is he doing?

Kristine



Please keep a close eye on him. I have a boy who had an allergic reaction to Metrodiazonal 6 years ago. We had given it to him for ongoing diarehha. This drug is the generic form of Flagyl. This can be a very good drug for most dogs but my boy had a sensitivity to the drug meaning that the usual dosage for his weight gave twice the reaction it should have. My vet, the emergeny vet & we ourselves were at a total loss at to what the problem was but he kept getting worse & worse. High temp of 106 degrees, lethargic, even got to the point where he couldn't even stand up let alone eat or drink. My vet sent us to Ohio State University as he was at a total loss as to what was causing these kind of reactions. To be honest with you, we would have lost him overnight due to the high fever had we not taken him to the emergency clinic for stabalization. At the university veterinary school they figured out the problem thru observation of him & questions to me. Thank goodness I had grabbed all the meds he had taken in the last 6 months when I headed down there. The reason he couldn't stand up was that the drug reaction gave him vertigo! His eyes were moving in opposite directions of each other. The specialist there told me not to be too hard on my vet as he could be in practice his entire life & never see this problem. But once he has seen it he will never forget it. The university gets about 4 cases a year & as he told me "remember we get all the whacko cases". So please make sure the dosage is correct for his weight. Reweigh him too. You may have to change the dosage as he may have lost some weight since he is not eating & drinking normally. If your dog does have a sensitivity to this drug it can be a very scary thing. I never thought I would bring my boy back home alive. But rest, flushing the drug out of his system & giving him valium took care of the problem. He was hospitalized at the university for 4 days before coming home. The emergency clinic thought at first he was having epileptic seizures. Then they thought he had encephalitis (sp). So this drug can give various types of reactions. MAKE SURE YOU LET THEM KNOW WHAT DRUGS HE HAS BEEN ON. I can't stress this enough. A sensitivity to this drug is not very common in our breed but the possibility is there. My dog is living proof of that as well as another friend's OES that lives in Utah. The MDR1 gene mutation is a real thing. I know this drug can be very effective in the high majority of our breed but for my dogs....I just won't give Flagyl (Metrodiazonal) again.
My question is this: Why do vets even bother with metronidozole if pancur is the one that kills the parasites? My dog has had two rounds of metronidazole and the diareahea has still re-occured. The Vet is currently testing for Giardhea and she said that if they do find it they would probably put her on a stronger dose of Metro? Why wouldn't my vet put her on Pancur since its obvious that she is not respnding to the other drug?

My poor dog has lost so much weight and she is till hangin in there.
CM wrote:
My question is this: Why do vets even bother with metronidozole if pancur is the one that kills the parasites? My dog has had two rounds of metronidazole and the diareahea has still re-occured. The Vet is currently testing for Giardhea and she said that if they do find it they would probably put her on a stronger dose of Metro? Why wouldn't my vet put her on Pancur since its obvious that she is not respnding to the other drug?

My poor dog has lost so much weight and she is till hangin in there.


I can't stress it enough.....make sure to get an accurate weight on your dog & dose it accordingly. Don't asume that what she weighs today will be what she weighs even 3 days from now.
Ask your vet if it would do any harm to try Panacur this time since the Metronicazole hasn't fixed the problem... or if there is a reason you shouldn't try it. You might also ask about adding a probiotic... some vets believe strongly in them, others don't.

You also need to be very strict about hygiene... pick up any poo as soon as it hits the ground, wash down the area or cover any soiled ground with sand/dirt if you can't clean it all up and wash fannies if they're messy.

Quote:
My poor dog has lost so much weight and she is till hangin in there.

If the problem isn't fixed soon, consider seeking a second opinion.
I want to thank everyone for the information concerning giardia. We recently adopted the most adorable little girl, Beagle. Yes, we found out today that she is infected with this bugger and coccia:( . Kiki is now taking Albon, Metronidazole, and Panacur. I am truly looking forward to my darling feeling better. Thank you again.

Roni
We went through the giardia mess this past winter. Everything kept coming back negative and my dog kept having more and more loose poop. Until one night when he kept "exploding" water loose stool several times in a row. I took him to emergency knowing he could dehydrate losing all that fluid so quickly.

He tested positive for giardia and was so dehydrated they had to keep him several days with IV fluids. He came home on flagyl but it took a few months, yes I aid months. before his poop firmed up to normal. Doc said he probably had the giardia a while but it is extremely difficult to detect.

They can pick giardia up from almost anywhere...stagnat water, puddles, dog parks, classes, etc. However you should clean thoroughly if its diagnosed and keep the butt clean as they can reinvest themselves with the "danglers" 8O
I just wanted to say my puppy is currently going through Giardia and so when the vet gave us Metronidazole also known as Flagyl me and my wife did some research to find that this is commonly used by vets in the treatment of worms. We also found out that it hasn't been approved for use on dogs and cats. I found several sites that said that it shouldn't be used on puppies for any reason. This drug has a long list of side effects one of them being liver failure and this can tend to take effect after 7 to 12 days of use of Metronidazole(Flagyl). How long was your puppy on this treatment. The cure may have been fatal. From what I have read the Panacur is pretty much the safest option and it should have been able to take care of the Giardia too.
I have a 3 year old rescued greyhound. We found out that he had hookworm, so the vet gave us panacur to give him. The day after we gave it to him, he didn't want to eat. I could hear his stomach growling, but he acted like he didn't feel good. He was drinking water though. I finally gave him some chicken soup that I made over a little small kibble dry dog food. He ate that right up. After he ate, he seemed to feel much better. He even ate his evening meal a couple of hours later. The next day we went through the same thing. It seemed that when his stomach was empty in the morning, it must have hurt or been nauseous. He would act lethargic and refuse to eat. The second day, I fixed a couple of scrambled eggs for him, and got him to eat those. Once he ate that, he was bounding around and felt better. He then ate his whole bowl of food. I don't know if its the panacur, or the worms themselves dying that are bothering him, but it seems that keeping him from getting an empty stomach is the key. His stools have been a little loose, but not too bad with the diarrhea. From what I've read, this stomach upset is supposed to be uncommon, but it certainly does happen with some dogs. You just want to make sure to keep them hydrated, and don't wait too long to get them to the vet if they're not eating and or drinking. Good Luck!
[Brenna is 4 months old and my daughter adopted her through acpca on july 16th 2011. on August 9th Brenna had a bowel and it had rice like worms she was taken to the vet and was given a med for dewrorming...I had to bring a sample of her stool in the following day, owever that eveing she had a bowel and it was apparent that she had another type of worm. I took the sample to the vet and sure enough she had to be treated with pancur. She was started with her med on the 12th and sat night she seemed quiet and not herself. I woke the next am to her being quiet and I took her out side as she usually is up and jumping and waigin her tail to go out. Her apetite was ok however sunday am I ook her put and she vomited and had loose stool. Brenna is not brenna to me and she seems to be tired and out of it. I have been reading alot of the same signs that Brenna has. She will play but I have to get her motivated to do so, she finally ate this evening enough to make ne feel beeter and did have a few sips of her water. I dont feel comfortable giving her the last two doses for she was given panacur 1 gram for a 10 lb dog, however the vet informed us to give her only half the packet for she is only 4.5 lbs. I have woke this morning with fer in my heart, she played this evening but is back in her cage lying down. I will be def calling in am, need to be speak to vet in regards to this even though I read pretty much the same about other dogs on here. Thank you all for your posts made me feel a little better knowing I am not alone.
Where did you adopt her from?
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